hydrolyzed-gelatin-beef-collagen-peptides The search for a peptide YY antibody is driven by the need to detect and study this significant peptide hormoneA Paneth cell antimicrobial peptide that maintains Candida gut .... Peptide YY (PYY), also known as Peptide tyrosine tyrosine, plays a crucial role in regulating appetite, inhibiting pancreatic secretion, and influencing gut motility(ab22663) Anti-Peptide YY/PYY antibody - Abcam. Researchers and scientists utilize antibodies specifically designed to bind to PYY to facilitate its detection in various biological samples and experimental assays. This article explores the key aspects of peptide YY antibodies, including their types, applications, and considerations for selectionPeptide YY Antibody (029-01-1): sc-80499.
Peptide YY is a 36-amino-acid peptide hormone primarily produced by enteroendocrine L-cells in the small and large intestines.Peptide YY (PYY) isa gut hormone that regulates appetite and inhibits pancreatic secretion. Peptide YY (PYY) can mediate its effects through the Neuropeptide Y ... It belongs to the neuropeptide Y (NPY) family of peptides. PYY is released postprandially (after a meal) and circulates in the bloodstream, signaling satiety to the brain by acting on hypothalamic neuropeptide Y receptorsPYY inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility (Ref: SWISS-Prot).. This action contributes to reducing food intake. Beyond its role in appetite regulation, PYY also exhibits inhibitory effects on exocrine pancreatic secretion and gastrointestinal motility. Understanding these physiological functions underscores the importance of having reliable tools, such as antibodies, to study PYY's presence and activity in biological systemsPeptide YY antibody(AA 29-64). This Rabbit Polyclonal antibody specifically detects Peptide YY in WB and IHC (p). It exhibits reactivity toward Rat and Mouse..
Peptide YY antibodies are available in various forms, differing in their host species, clonality, and conjugation. The choice of antibody is critical for successful experimental outcomes.Human Peptide YY Antibody MAB94563
* Host Species: Antibodies can be raised in different animals, such as rabbits, mice, or chickens. For example, a rabbit polyclonal Peptide YY/PYY antibody is a common option, as are mouse monoclonals.24294-1-AP targets peptide YYin WB, IF, IHC, ELISA applications and shows reactivity with human samples. The host species can influence cross-reactivity and the optimal experimental conditionsPeptide YY(PYY), a secretory peptide, is expressed by L cells (enteroendocrine cells) in the small and large intestine, Islet of Langerhans cells, testis, and ....
* Clonality: Antibodies are either polyclonal or monoclonal.
* Polyclonal antibodies, like the rabbit polyclonal Peptide YY/PYY antibody, are a mixture of antibodies that recognize multiple epitopes on the PYY molecule. They can offer broader detection but may have higher background noise.
* Monoclonal antibodies, such as an IgG1 mouse monoclonal Peptide YY antibody, recognize a single, specific epitope. This specificity generally leads to cleaner results and greater consistency, making them invaluable for precise research applications.
* Conjugation: Some antibodies are conjugated to fluorescent dyes (e.peptide YY (PYY) Antibodyg., PerCP) or other labels, which are essential for specific detection methods like flow cytometry or immunofluorescence. For instance, Peptide YY Antibody (1) [PerCP] is designed for such applications.
The primary use of a peptide YY antibody is in the detection and quantification of PYY in biological samples.Rabbit Polyclonal Peptide YY/PYY antibody. Suitable for IHC-FoFr, IHC-P and reacts with Rat, Mouse samples. Cited in 23 publications. This enables researchers to investigate its physiological and pathological roles. Common applications include:
* Immunohistochemistry (IHC): This technique allows for the visualization of PYY expression within tissue sections, helping to identify the cells and locations where PPY is produced or acting. Antibodies like the rabbit polyclonal Peptide YY/PYY antibody are frequently cited in IHC studies.
* Western Blotting (WB): WB is used to detect specific proteins in a sample based on their molecular weight. A peptide YY antibody can confirm the presence and size of PYY in cell lysates or tissue extracts.Anti-Pyy Antibody Products
* Enzyme-Linked Immunosorbent Assay (ELISA): ELISA kits, such as the Human Peptide YY / PYY ELISA Kit, are widely used for the quantitative measurement of PYY levels in biological fluids like serum or plasma. These kits leverage antibodies to provide sensitive and accurate quantificationPeptide YY antibody(AA 29-64). This Rabbit Polyclonal antibody specifically detects Peptide YY in WB and IHC (p). It exhibits reactivity toward Rat and Mouse..
* Immunofluorescence (IF): Similar to IHC, IF uses fluorescently labeled antibodies to detect PYY within cells or tissues, allowing for microscopic localization.Target protein:peptide YY; Target gene: PYY; Verified species reactivity: Human; Interspecies information: Highest antigen sequence indentity to the following ...
When choosing a peptide YY antibody, several factors should be considered to ensure optimal performance and reliable results:
* Target Specificity: Ensure the antibody is highly specific for Peptide YY and does not cross-react with other related peptides, such as NPYPeptide YY (PYY), Chicken Polyclonal Antibody. Some antibodies may be designed to recognize specific isoforms or fragments, like PYY(3-36), which is known for its potent inhibition of food intake.
* Reactivity: Verify that the antibody has been tested and validated for reactivity with the species of interest (e.gAnti-Peptide YY antibody [04] (GTX60990)., human, rat, mouse).
* Application Suitability: Confirm that the antibody is validated for the intended experimental application (e.g., IHC, WB, ELISA)Peptide YY/PYY Antibody PB10014.
* Supplier Reputation and Citations: Opt for antibodies from reputable suppliers and check for publications that have successfully used the antibody作者：JF Pierre·2023·被引用次数：83—We have found thatpeptide YY(PYY1-36 ), but not endocrinePYY3-36 , acts as an antimicrobial peptide (AMP) expressed by gut epithelial paneth cells (PC).. This provides real-world validation of its performance.Anti-Peptide YY Antibody from chicken, purified by affinity ...
In conclusion, peptide YY antibodies are indispensable tools for researchers studying appetite regulation, gastrointestinal physiology, and related metabolic disorders. By understanding the different types of antibodies available and their specific applications, scientists can select the most appropriate reagent to advance their research goals.
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